Quality of life by age, sex and body mass index

Just a quick post on some data reported in Section 6 of NICE Clinical Guideline 43 (originally from a 2004 publication by Macran) which reports quality of life (QoL) by sex, and BMI and age brackets:1Macran S. The Relationship between Body Mass Index and Health-Related Quality of Life. 190. 2004. York, The Publications Office, Centre for Health Economics. Centre for Health Economics Discussion Paper.

NICE CG43 QoL Figure

The only unexpected aspect of the data is the high QoL in males with BMI greater than 40 aged 25-34 and females aged 18-24, but that’s likely driven by low sample size. Otherwise, there’s a general downward trend with age and an inverted J-shaped curve with respect to BMI, which approximately mirrors the J-shaped curves observed when plotting BMI against mortality 2Berrington de Gonzalez A, Hartge P, Cerhan JR et al. Body-mass index and mortality among 1.46 million white adults. N Engl J Med. 2010;363(23):2211–9.,3Tobias DK, Pan A, Jackson CL et al. Body-mass index and mortality among adults with incident type 2 diabetes. N Engl J Med. 2014;370(3):233–44.,4Dudina A, Cooney MT, Bacquer DD et al. Relationships between body mass index, cardiovascular mortality, and risk factors: a report from the SCORE investigators. Eur J Cardiovasc Prev Rehabil. 2011;18(5):731-42. and certain diabetes complications.5Sohn MW, Budiman-Mak E, Lee TA, Oh E, Stuck RM. Significant J-shaped association between body mass index (BMI) and diabetic foot ulcers. Diabetes Metab Res Rev. 2011;27(4):402–9.

References   [ + ]

1. Macran S. The Relationship between Body Mass Index and Health-Related Quality of Life. 190. 2004. York, The Publications Office, Centre for Health Economics. Centre for Health Economics Discussion Paper.
2. Berrington de Gonzalez A, Hartge P, Cerhan JR et al. Body-mass index and mortality among 1.46 million white adults. N Engl J Med. 2010;363(23):2211–9.
3. Tobias DK, Pan A, Jackson CL et al. Body-mass index and mortality among adults with incident type 2 diabetes. N Engl J Med. 2014;370(3):233–44.
4. Dudina A, Cooney MT, Bacquer DD et al. Relationships between body mass index, cardiovascular mortality, and risk factors: a report from the SCORE investigators. Eur J Cardiovasc Prev Rehabil. 2011;18(5):731-42.
5. Sohn MW, Budiman-Mak E, Lee TA, Oh E, Stuck RM. Significant J-shaped association between body mass index (BMI) and diabetic foot ulcers. Diabetes Metab Res Rev. 2011;27(4):402–9.